Yes it is a little bit late, but here is my best of 08 list:
Film:
Synechdoche, NY
Milk
Burn After Reading
Music:
Failures- S/T
True Widow - S/T
These Arms Are Snakes - "Tail Swallower and Dove"
Trap Them - "Seizures In Barren Praise"
Blacklisted - "Heavier than Heaven, Lonelier than God"
Young Widows - "Old Wounds"
Pygmy Lush - "Mount Hope"
Cold Cave - "Coma Potion" as well as "The Trees Grew Emotions and Died"
I'm sure there are a lot of things I forgot, but I'm not in the right mood to do this.
What I am really looking forward to this year is-
New Kylesa
New Converge
hopefully new Coliseum
and a bunch of other stuff...